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Phase III HCVerso™ trial design focuses on genotype-1b patients following positive Phase IIb data in this population


INGELHEIM, Germany - Thursday, January 17th 2013 [ME NewsWire]

(BUSINESS WIRE)-- For media outside of the U.S.A., UK and Canada only

Today, Boehringer Ingelheim announced that the first patients have been enrolled in the company’s pivotal Phase III interferon (IFN)-free hepatitis C (HCV) clinical trial programme, HCVerso™. Boehringer Ingelheim’s IFN-free investigational polymodal* regimen combines faldaprevir (BI 201335)+, a next wave once-daily protease inhibitor, and BI 207127+, a non-nucleoside polymerase inhibitor, plus ribavirin.

The HCVerso™ clinical trial programme includes two Phase III IFN-free clinical trials that will treat approximately 1,000 treatment-naïve HCV genotype-1b (GT-1b) patients.1,2The decision to focus the Phase III trials on this patient group follows positive Phase IIb trial data from the SOUND-C studies, where B ... Read more »
Views: 128 | Added by: uaeonlinenews | Date: 01.19.2013

Reduces switching time to one-third of existing product

TOKYO - Thursday, January 17th 2013 [BUSINESS WIRE/ ME NewsWire]

Toshiba Corporation (TOKYO:6502) has launched a discrete IGBT for the strobe lighting of digital cameras that reduces switching time to one-third that of Toshiba's current product. The new IGBT, "GT5G134", was developed as a dedicated solution for photo-flash intensity control and high-speed-switching photo flash applications.
 

Key Features

1.
          

High-speed switching: tf = 0.6μs (typ.) @IC=110A

2.
          

Low saturation voltage: VCE(sat) = 2.2V (typ.) @IC=110A

3.
          

Low gate driving voltage: VGE = 4.0V (min.) @IC=110A

4.
          

Peak collector current: ICP = 110A (max)

5.
      &nb ... Read more »
Views: 128 | Added by: uaeonlinenews | Date: 01.19.2013

New research programme unveiled by Boehringer Ingelheim and the European Foundation for the Study of Diabetes (EFSD) invites European diabetes research projects to apply for funding

INGELHEIM, Germany - Thursday, January 17th 2013 [ME NewsWire]

(BUSINESS WIRE)-- The Boehringer Ingelheim and EFSD diabetes partnership has opened submissions for diabetes research grant applications from across Europe. In a collaboration which aims to stimulate and accelerate European research in diabetes, the EFSD/Boehringer Ingelheim European Diabetes Research Programmes have dedicated more than 2.5 million euros over three years to support research projects targeting specific areas of interest.

"Diabetes affects more than 371 million people worldwide and diabetes remains undiagnosed in up to 50% of cases,” said Prof. Klaus Dugi, Corporate Senior Vice President Medicine, Boehringer Ingelheim. "We are delighted to partner with the EFSD on this initiative and hope the grant encourages ... Read more »
Views: 107 | Added by: uaeonlinenews | Date: 01.17.2013

Submission is based on the LUX-Lung 3 trial, which is the largest (n=345) registration study to date in patients with EGFR (ErbB1) mutation positive non-small cell lung cancer (NSCLC)

INGELHEIM, Germany - Wednesday, January 16th 2013

(BUSINESS WIRE/ ME NewsWire)-- For NON-U.S. Media Only

Boehringer Ingelheim today announced that the New Drug Application (NDA) for its investigational oncology compound afatinib* has been accepted for filing and granted Priority Review by the U.S. Food and Drug Administration (FDA). The application for afatinib* is currently under review for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation as detected by an FDA-approved test. The FDA target action date for afatinib* will be in the third quarter of 2013.

Afatinib has demonstrated a significant delay in tumour growth versus the best-in-class chemotherapy, which resulted in 11 ... Read more »
Views: 108 | Added by: uaeonlinenews | Date: 01.17.2013

The OneShot™ Renal Denervation Device Offers a Solution for Physicians treating Patients with High Blood Pressure who Fail Drug Therapy

 

MANSFIELD, Mass. - Thursday, January 17th 2013 ... Read more »

Views: 196 | Added by: africa-live | Date: 01.17.2013 | Comments (0)

Adds two new hires in London

ME Newswire / Business Wire

LONDON - Wednesday, January 16th 2013

BTIG Limited, the European affiliate of BTIG, LLC, a global financial services firm specializing in institutional trading and related brokerage services, is expanding its London office with the hiring of two experienced sales traders: Margie Sadleir and Daniel Muller.

"Building on the additions we made in 2012, these new hires in London will help us to better serve clients in Europe,” said Matt Cyzer, President and Head of European Equities for BTIG, Ltd. "With emerging markets and other European sectors being a focus with many of our clients, Margie and Daniel expand BTIG’s range of client coverage and trading opportunities.”

Margie Sadleir joins BTIG as a senior emerging markets sales trader. She most recently worked at CA Cheuvreux, where she helped launch the emerging markets business. Sadlier, who has 12 years of sales trading experience, also worked f ... Read more »
Views: 130 | Added by: uaeonlinenews | Date: 01.17.2013

NEW YORK - Wednesday, January 16th 2013 [ME NewsWire]

(BUSINESS WIRE)-- Starr Companies announces the appointment of Jeffrey Hayman to the position of President of International Insurance Operations.

Mr. Hayman will be responsible for the overall growth, profitability, distribution, and product offerings outside of the United States. Mr. Hayman will report directly to Maurice R. Greenberg, Chairman and Chief Executive Officer of Starr Insurance Holdings, Inc.

"Jeff possesses a strong understanding of international business and his experience, particularly in Asia, is a unique fit for our organization. As part of our senior team, we expect that he will contribute to our continued growth in the international marketplace,” states Mr. Greenberg.

Mr. Hayman added: "I am excited to join Starr, an organization with a strong growth trajectory and a talented team of insurance leaders. I look forward to joining the organization and contributing to its success.”

... Read more »
Views: 111 | Added by: uaeonlinenews | Date: 01.17.2013

TOKYO - Tuesday, January 15th 2013 [ME NewsWire]

(BUSINESS WIRE)-- Toshiba Corporation (TOKYO:6502) has launched a low ON-resistance power MOSFET as the latest addition to its TO-220SIS package series for automotive applications. The new product, "TK80A04K3L", also achieves low leakage current and guarantees operation at 175°C. While it is primarily suited to automotive applications, it can also be used in motor drives and switching regulators.
 

Polarity
          

Part number
          

Drain-to-source voltage VDSS (V)
          

Drain Current ID (A)
          

Series

Nch
          

TK80A04K3L
          

40
          

80
     &n ... Read more »
Views: 123 | Added by: uaeonlinenews | Date: 01.16.2013

RESEARCH TRIANGLE PARK, N.C. - Wednesday, January 16th 2013 [ME NewsWire]

(BUSINESS WIRE)-- Quintiles announced today that it has been named to the CSO40 by IDG's CSO magazine for its groundbreaking work establishing highly secure infrastructure.

CSO is a premier content and community resource for security decision makers leading "business risk management” efforts within their organizations. Quintiles was selected for the CSO40 awards based on its "Secure Infrastructure for China” entry.

The CSO40 Awards recognize a select group of 40 organizations that have demonstrated how their security projects / initiatives have created outstanding business value and thought leadership for their companies. The CSO40 Awards are scored according to a uniform set of criteria by a panel of judges that includes security leaders, industry experts, and academics.

Quintiles IT Innovation in China

Quintiles’ expansion and growth in China required a unique approach to meet ... Read more »
Views: 120 | Added by: uaeonlinenews | Date: 01.16.2013

More than 3 times faster than previous models, enhanced valves will help manufacturers increase production, improve quality and reduce costs

EAST PROVIDENCE, R.I. - Tuesday, January 15th 2013 [ME NewsWire]

(BUSINESS WIRE)-- Nordson EFD, a Nordson company (Nasdaq: NDSN), announces that they have more than tripled the speed of their PICO™ series jet dispensing systems—from 150Hz (cycles per second) up to an industry-leading continuous 500Hz, making the new and improved versions the fastest piezoelectric valves available to the global manufacturing community.

"Making our proven PICO valve technology even faster is the latest demonstration of our 50 years of commitment to developing innovative dispensing technologies that help our customers build their own products better, faster and more cost-effectively,” according to Ken Forden, Nordson EFD’s Vice President and General Manager. "The fact that the enhanced PICO valves can run continuously at such high speed will ena ... Read more »
Views: 124 | Added by: uaeonlinenews | Date: 01.16.2013 | Comments (0)

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