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HIGH POINT, N.C. - Thursday, August 15th 2013 [ME NewsWire]

(BUSINESS WIRE)-- TransTech Pharma, Inc. announced today important clinical trial data for its new diabetes drug. TTP399, a novel, liver-selective glucokinase activator (GKA), demonstrated clinical evidence of normalizing HbA1c without inducing hypoglycemia in type 2 diabetic subjects on stable doses of metformin. TTP399 is the first liver-selective GKA that shows no GKA activation in the pancreas and does not interrupt the binding of glucokinase (GK) with the GK regulatory protein (GKRP).

TTP399 has completed a 6-week, multi-center, phase 2a study in type 2 diabetic subjects on stable doses of metformin. TTP399 treatment led to a reduction in HbA1c of 0.92 (p< 0.001) and 0.53 (p< 0.001) placebo-corrected. In addition, 100% of subjects on drug with a starting HbA1c baseline of 7.5% or less achieved the American Diabetes Association’s goal of reducing HbA1c values to 7% or less, and up to 85% of those subjec ... Read more »
Views: 273 | Added by: uaeonlinenews | Date: 08.17.2013

HONG KONG. - Friday, August 16th 2013 [ME NewsWire]

Rapid PC Plus transformation fueled by solid growth from PC and PC Plus businesses

    Ranked #1 PC maker in the world for the first time ever
    Ranked #3 supplier of smart-connected devices (smartphones, tablets and PCs) worldwide
    Pre-tax income of US$215 million and earnings of US$174 million
    Revenue of US$8.8 billion
    Basic EPS of 1.67 US cents, or 12.96 HK cents
    Net cash reserves of US$3.1 billion (as of June 30, 2013)

(BUSINESS WIRE) Lenovo Group today reported results for its first fiscal quarter ended June 30, 2013, with quarterly revenue of US$8.8 billion, a ten percent increase year-over-year. At the same time, Lenovo’s first quarter pre-tax income increased 16 percent year-over-year to US$215 million, while earnings grew 23 percent year-over-year to US$174 million, highlighting the Co ... Read more »
Views: 239 | Added by: uaeonlinenews | Date: 08.17.2013

Linagliptin demonstrated clinically important HbA1c reduction, safety and tolerability profile in elderly people with Type 2 Diabetes with inadequate glycaemic control

INGELHEIM, Germany & INDIANAPOLIS, US - Thursday, August 15th 2013 [ME NewsWire]

(BUSINESS WIRE)-- For Non-US and Non-UK Media

Data published in The Lancet showed that elderly people with Type 2 Diabetes (T2D) treated for 24 weeks with the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin, marketed by Boehringer Ingelheim and Eli Lilly and Company, experienced significant reductions in blood glucose levels (HbA1c) compared with those receiving placebo. In addition, the overall safety and tolerability profile of linagliptin was similar to placebo, with no significant difference in hypoglycaemia.1

"Elderly individuals comprise approximately 15% of people with Type 2 Diabetes2; however, few glucose-lowering agents have been investigated in this group. This evidence gap hinders clinical de ... Read more »
Views: 223 | Added by: uaeonlinenews | Date: 08.17.2013 | Comments (0)

Acquisition bolsters Quintiles’ small biopharma, oncology and medical device capabilities

RESEARCH TRIANGLE PARK, N.C - Thursday, August 15th 2013 [ME NewsWire]

(BUSINESS WIRE) To stay ahead of the diverse and evolving needs of its global customer base, Quintiles today announced it has signed an agreement to acquire Novella Clinical (Novella), a full-service clinical research organization (CRO) focused primarily on emerging oncology customers as well as those in the medical device and diagnostics sectors.

"The expertise and insight the Novella team brings will be a strong addition to our existing capabilities and help further differentiate Quintiles in an increasingly competitive marketplace,” said Paula Brown Stafford, President, Clinical Development at Quintiles. "Novella’s understanding of emerging companies, as well as our shared commitment to quality, customer service, and above all, the patients we ultimately serve, makes this acquisition a good fit for both ... Read more »
Views: 213 | Added by: africa-live | Date: 08.17.2013 | Comments (0)