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OSAKA, Japan & PASADENA, Calif. - Tuesday, 28. June 2022
− Fibrosis regression observed in 58% (7 of 12) of patients receiving 200 mg fazirsiran

− Median reduction of 83% of Z-AAT accumulation in the liver

− Reduction of 69% in histologic globule burden

− Substantial and sustained improvements in clinically relevant biomarkers of liver health

(BUSINESS WIRE) -- Takeda (TSE:4502/NYSE:TAK) (“Takeda”) and Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced that results from a Phase 2 clinical study (AROAAT-2002) of investigational fazirsiran (TAK-999/ARO-AAT) for the treatment of liver disease associated with alpha-1 antitrypsin deficiency (AATD) were recently published in the New England Journal of Medicine (NEJM) and presented in an oral presentation at The International Liver Congress™ 2022 - The Annual Meeting of the European Association for the Study of the Liver (EASL). The NEJM article ... Read more »

ZUG, Switzerland - Wednesday, 22. June 2022 AETOSWire

    Prurigo nodularis is a rare, potentially debilitating, inflammatory skin disease characterized by disfiguring skin nodules often covering extensive areas of the body, and an intense and chronic itch

    There are currently no approved therapeutic options

    Nemolizumab is a first-in-class investigational monoclonal antibody that blocks the signaling of IL-31, a key neuroimmune cytokine involved in the pathogenesis of prurigo nodularis

    This phase III trial met both primary endpoints, confirming nemolizumab monotherapy significantly improved skin lesions and pruritus (itch) in adult prurigo nodularis patients

    The trial also met all key secondary endpoints, with a safety profile consistent with the phase II trial results

(BUSINESS WIRE) -- Galderma today announced the phase III OLYMPIA 2 tria ... Read more »

(BUSINESS WIRE) -- PUMA has entered New Tokyo, the virtual city 10KTF calls home. The shop is known for its streetwear offerings and is owned by Wagmi-san, a digital artisan whose collections and NFT community recently welcomed the global sports brand.

News of the partnership was shared at an event hosted by 10KTF last night in New York. Their event was one of many hosted during the week of NFT.NYC, a conference attended by crypto industry professionals, traders, and other web3 enthusiasts. The official announcement confirms weeks of speculation after PUMA tweeted a video previewing the new release of a classic sneaker. Camouflaged in the video is a frame with the shop’s logo and Wagmi-san at his storefront. Despite how hidden it may have been, the subtle clue was quickly discovered and fueled conversations around its meaning for 10KTF collectors.

“PUMA values the extremely engaged and passionate community that Wagmi-san has nurtured,” said Adam Pet ... Read more »

(BUSINESS WIRE) -- On the occasion of the Qatar Economic Forum (QEF), an annual event organized by Bloomberg and gathering thousands of participants from June 20 to 22, the President of the Togolese Republic, H.E. Faure Essozimna Gnassingbé, participated in a session focused on the socio-economic, security and industrial context of the West African States, entitled "In Conversation with President Gnassingbe”.

This second edition of the Qatar Economic Forum (QEF), an event organized by Bloomberg from June 20 to 22 at the Ritz-Carlton Hotel in Doha, focused on the theme of a balanced global economic recovery. The panel session featuring H.E. Faure Essozimna Gnassingbe, entitled "In Conversation with President Gnassingbe", focused on Togo's socio-economic context, the progress made in development despite the health crisis, but also the concerns raised by inflation and insecurity.

“The first issue that we do have, as you know, is the conseq ... Read more »